Broadly Neutralizing Antibodies (bNAbs)

Antibodies are protective proteins produced by your immune system. They attach to antigens (foreign substances) and remove them from your body.

Broadly neutralizing antibodies (bNAbs) was a type of antibody discovered in the 1990s from a small subset of HIV-infected individuals

They can recognize and block many types of human immunodeficiency virus (HIV) from entering healthy cells. 

They may also activate other immune cells to help destroy HIV-infected cells. 

Researchers are investigating whether bNAbs could be used to develop a therapeutic HIV vaccine.

The germline-targeting strategy is the one approach where immunologists are using for development of B Cell based HIV vaccine.

Germline-targeting